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One of the most important goals of clinicians is patient comfort.

When patients present to the emergency department (ED), treating the pain and anxiety that accompany the chief complaint are critical to patient satisfaction and quality of care.

This is accomplished along a continuum of sedation levels: Prior to the administration of medications, clinicians must know the level of sedation required for a given procedure and the appropriate dose of the pharmacologic agent or agents chosen.

Without sedation, stressful situations can lead to restlessness, and when a dog is restless it is more prone to hurt itself, not eat, hide and hurt or bite other people and animals.

sedate - dignified and somber in manner or character and committed to keeping promises; "a grave God-fearing man"; "a quiet sedate nature"; "as sober as a judge"; "a solemn promise"; "the judge was solemn as he pronounced sentence"serious - concerned with work or important matters rather than play or trivialities; "a serious student of history"; "a serious attempt to learn to ski"; "gave me a serious look"; "a serious young man"; "are you serious or joking?

Falls, hip fractures, delirium, and urticaria lead the list of preventable adverse drug events.1 About one in three older persons taking at least five medications will experience an adverse drug event each year, and about two thirds of these patients will require medical attention.2 Approximately 95 percent of these reactions are predictable, and about 28 percent are preventable.3Although adverse drug reactions tend to be unexpected in younger persons, many reactions in older adults are exaggerations of expected physiologic effects of the drugs.

A number of unique and important pharmacokinetic changes in older adults, which have been covered in detail elsewhere, have been postulated as the reasons for such observations.4However, age is not the only risk factor for an adverse drug reaction in older patients.5 Preventable adverse drug events in older adults are often the result of misuse, overuse, or underuse of medications.6 This review summarizes interventions for reducing inappropriate prescribing to older adults in the community and in skilled nursing facilities and the evidence, where available, to support these interventions.

Authors, for example, sometimes talk about how the characters can come to life and write the story for them.