The rate of diversification for 12 out of the 15 subjects was comparable to the neutral evolution rate.
While temporal diversification was consistent with evolution patterns in the absence of selection, mutations from the founder virus were highly clustered on statistically identified selection sites, which diversified more than 65 times faster than non-selection sites.
While total-evidence dating uses the morphological data from the fossil record and morphological and sequence data from extant taxa together to infer the tree and divergence times.
The age of each fossil is assigned a prior distribution directly.
In addition, they suggested that this uniform rate of a specific protein would be approximately constant, not just over evolutionary time, but also across different lineages or taxonomic groups.