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Aloe Vera has perhaps the longest recorded history of therapeutic use in humans and animals, dating back to the 16th century BC.

It remains one of the best-known and commonly used herbs in the U. today, and is applied to the skin topically as well as ingested orally for a variety of conditions.

The clear, mucilaginous gel inside the leaves contains a host of incompletely understood but actively researched bioactive substances including vitamins, minerals, amino acids, and enzymes, as well as lignans, glycoproteins such as lectin, flavonoids, polysaccharides, carotenes, and many others.