Here we show that a similar strategy is equally effective in the disruption of appetitive pavlovian cue–food memories.
However, systemic administration of the NMDA receptor partial agonist D-cycloserine, under the same behavioural conditions, did not potentiate appetitive memory extinction, suggesting that reactivation does not enhance subsequent extinction learning. collected and analysed data and contributed to writing the paper.
Here we show that the spatial context plays a unique role for this type of memory updating: Being in the same spatial context during original and new learning is both necessary and sufficient for the incorporation of new information into existing episodic memories.
Memories are automatically reactivated when subjects return to an original learning context, where updating by incorporating new contents can occur.
Various aspects of the phenomenon have been described in cognitive psychology, but no unifying theoretical account exists that explains memory updating and its triggers.